|
| Friday, 24 April 2020, 16:22 HKT/SGT | |
| |
|
|
|
|
| Prominent Advantages of Core Products |
HONG KONG, Apr 24, 2020 - (ACN Newswire) - Though the COVID-19 pandemic has blanketed the capital market in 2020, biotech stocks have stood out. Pharmaceutical stocks have become popular ones in the capital market as people pay more attention to health due to the pandemic. Many biotech companies have planned for IPO in Hong Kong this year. Akeso Inc. (the "Company", 9926.HK), a leading biopharmaceutical company in China, has been listed on the Stock Exchange of Hong Kong (HKEX) today. Akeso, Inc. (9926.HK) has attracted much market attention since its IPO. It is said that Akeso locked up a record about HK$165 billion, possibly crowning it the king of frozen capital this year. It is reported that before the listing, Akeso introduced nine cornerstone investors who subscribed for USD163 million of shares in total. Fidelity Investment, who provides world-class, long-term investment solutions, and Lake Bleu Capital, who is specialising in healthcare investment, led the cornerstone investment, while international reputable investment funds and healthcare specialists like OrbiMed Funds, Boyu Capital, and Hudson Bay participated in it, which has constituted the strongest group of investors in recent years. Akeso was listed on the Hong Kong Stock Exchange today.
Efficient R&D Platform and Strong R&D Strength
The Company is dedicated to finding solutions to treat tumors and immunological diseases. It is generally known that it takes years to develop a new drug. However, the Company has over 20 drug development programs developed in-house though it has been established for only eight years. These programs include 12 antibodies in clinical-stage development, six bi-specific antibodies (two of which are at the clinical stage), and four antibodies with IND approvals from the Food and Drug Administration (FDA). Its product pipelines cover several major diseases, such as tumors, immunological diseases, and cardiovascular diseases. It is worth mentioning that the Company has developed all its programs in-house. In November 2015, the Company became the first China-based biotech company to out-license a fully internally discovered monoclonal antibody to a world-leading pharmaceutical company as it out-licensed its CTLA-4 monoclonal antibody drug candidate (AK107) to Merck for a total consideration of up to USD200 million.
The Company's strong R&D capability is indispensable from its end-to-end ACE Platform that possesses comprehensive, the most cutting-edge functionalities in developing therapeutic antibodies. The ACE Platform encompasses drug development and manufacturing and enables seamless technology transfer from drug discovery and CMC to manufacturing. Moreover, it holds strong internal manufacturing capacity that is compliant with GMP standards regulated by the NMPA, FDA and EMA. All drugs in the clinical stage are produced in the Company's proprietary facilities in line with GMP standards.
Prominent Advantages of Core Products, Favored by the Capital Market
The key to biopharmaceutical success lies in R&D strength and efficiency. The player who takes the lead to develop a drug and obtain approval for launch, and who can prove commercialization capabilities will gain competitive edges.
The Company has developed industry-leading drugs with the ACE Platform including its core products: PD-1/CTLA-4 bi-specific antibody (AK104) and PD-1 monoclonal antibody drug, Penpulimab (AK105). Its products also encompass AK101, a promising monoclonal antibody against autoimmune diseases, and AK102 that has high potential to become the first cardiovascular drug candidate against PCSK9 developed in China.
The Company has led the world in terms of the R&D of bi-specific antibodies. Bi-specific antibodies are deemed as a second-generation antibody therapy against tumors. With respect to the research on bi-specific antibodies, the Company possesses the unique bifunctional antibody technology, Tetrabody, making it one of the few bi-specific antibody platforms verified in both manufacturing and clinical stage. According to clinical observation, compared with the combined therapy of Nivolumab and Ipilimumab, AK104 has demonstrated better safety and efficacy. As of September 30, 2019, over 90 bi-specific antibodies were undergoing clinic trial. Nevertheless, no PD-(L)-based bi-specific antibodies had been approved for market launch. AK104 is the world's first bi-specific antibody drug that is in the clinical trial stage. It is expected that the first new drug application (NDA) of AK104 of the Company for treating cervical cancer will result in first-mover advantage.
AK105 of the Company is a monoclonal antibody currently in late-stage clinical development. PD-1 monoclonal antibody drugs are experiencing fierce competition, as six PD-1 drugs have been launched in China. Despite the extensively competitive market, AK105 is still favored for its strong efficacy and high safety. Therefore, Sino Biopharmaceutical Limited, a HK-listed pharmaceutical leader, has cooperated with the Company to jointly develop and commercialize AK105. AK105 of the Company is the only PD-1 antibody that Sino Biopharm can use to develop PD-1-based monotherapy or combination therapy, which evidences the great commercial potential of AK105. After the new drug is launched, the wide online sale channels and immense commercial capability of Sino Biopharmaceutical Limited will be utilized by the Company to maximize the commercial value of AK105.
Thanks to its strong R&D strength and commercialization capabilities, the Company has been favored by the capital market. Through Series D financing in November last year, the Company raised USD126 million in total, with the leading investor being Sino Biopharmaceutical Limited. Medical funds like Lake Bleu Capital, OrbiMed, and AIHC Capital participated in the financing. The Company's valuation reached USD836 million after Series D financing and became nearly 18 times as high as that after Series A financing of RMB330 million in just four years. Especially, Shenzhen Capital Group Co., Ltd. (SCGC), a leading venture capital firm in China that was co-founded by the Shenzhen Municipal Government and a group of private partners, participated in every series of financing. Relevant funds under K. Wah Group became a shareholder of Akeso in the series of financing before the IPO. This also means that K. Wah Group has set foot in the healthcare sector. Investment from famous capital holders reflect Akeso's bright future.
Topic: Press release summary
Sectors: Daily Finance, Daily News, BioTech, Healthcare & Pharm
http://www.acnnewswire.com
From the Asia Corporate News Network
Copyright © 2025 ACN Newswire. All rights reserved. A division of Asia Corporate News Network.
|
|
|
|
|
|
|
Latest Press Releases
Olympus Launches New Surgical Energy Device for Hemostatic Cutting and Vessel Sealing 
Tuesday, October 21, 2025 10:00:00 PM
|
|
|
MHI Thermal Systems to Launch New 2026 Models of the S Series High-Capacity Residential-Use Air-Conditioners for the Japanese Market
Tuesday, October 21, 2025 9:10:00 PM
|
|
|
Foundry Welcomes Gregory Anderson as Global Chief Revenue Officer
Oct 21, 2025 21:00 HKT/SGT
|
|
|
New Land Cruiser "FJ" Makes World Premiere
Tuesday, October 21, 2025 8:29:00 PM
|
|
|
Sharp Initiates Collaboration with ARAV Corporation for Remote Control Solutions of Construction Machinery Utilizing Satellite Communication
Tuesday, October 21, 2025 8:00:00 PM
|
|
|
Hong Kong Tech Pavilions at GITEX Global 2025 tap into opportunities in the Middle East
Oct 21, 2025 19:50 HKT/SGT
|
|
|
Hitachi and OpenAI form strategic partnership centered on global AI data center expansion
Tuesday, October 21, 2025 7:06:00 PM
|
|
|
17th Hong Kong International Wine & Spirits Fair opens next month
Oct 21, 2025 18:50 HKT/SGT
|
|
|
Air T Enters into Agreement with Regional Express Holdings Limited
Oct 21, 2025 18:00 HKT/SGT
|
|
|
Indonesia's Legacy in the Global Vaccine Landscape: Bio Farma and DCVMN Strengthen Health Resilience through Global Partnership
Tuesday, October 21, 2025 3:45:00 PM
|
|
|
|
|
More Press release >> |
|
 |
|
|
|
|
 |
|
